Meclizine is used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness.

It may also be used to reduce lightheadedness, dizziness, and loss of balance (vertigo) caused by diseases that affect the inner ear.

Meclizine acts as a central nervous system depressant. It is believed its therapeutic actions occur due to the drug's drying effects and its ability to depress conduction of nerve messages in the inner ear.

It is most effective if taken before symptoms appear. Meclizine begins working about one hour after ingestion. It continues being effective for 8 to 24 hours.

 

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